Hadine Joffe, MD MSc

Executive Director, Mary Horrigan Connors Center for Women’s Health and Gender Biology

Executive Vice Chair for Academic and Faculty Affairs, Department of Psychiatry

Brigham and Women’s Hospital

Paula A. Johnson Professor of Psychiatry in the Field of Women’s Health

Harvard Medical School

Hadine Joffe MD MSc is the Paula A. Johnson Endowed Professor of Psychiatry in the Field of Women’s Health at HMS, as well as the Executive Vice Chair for Academic and Faculty Affairs in the Department of Psychiatry and the Executive Director of the Connors Center for Women’s Health and Gender Biology the at BWH, where she directs the Women’s Hormones and Aging Research Program. She is affilitated with the HMS Division of Sleep Medicine, the Dana Farber Harvard Cancer Center Breast Cancer Program, and the Department of Psychosocial Oncology and Palliative Care at the Dana Farber Cancer Institute.

Dr. Joffe received her undergraduate degree from Harvard University, her medical degree from Cornell University Medical College, and her master’s degree in Epidemiology from the Harvard School of Public Health.  She completed her psychiatry residency training at McLean Hospital and a fellowship in Reproductive Psychiatry at Massachusetts General Hospital. 

Dr. Joffe is an experienced clinician and clinical reproductive neuroscientist in the field of women’s brain health in relation to midlife aging, mental health, and neurobehavioral consequences of cancer therapies.  Her research has been continuously funded by the NIH since 2000, as well as by foundations and pharmaceutical companies. She is currently the PI of a U54 SCORE Center grant and 2 active R01s. Her work focuses on the mechanisms (neural, hormonal, stress, autonomic), course, downstream consequences (body fat gain), and treatment of neuropsychological symptom outcomes (depression, insomnia thermoregulatory disturbance, fatigue) in healthy midlife women and breast cancer survivors.

As the Director of the BWH Connors Center for Women’s Health and Gender Biology, Dr. Joffe oversees a comprehensive cross-departmental research program for the hospital with two main pillars — equity in the development of novel therapeutics for diseases that affect women exclusively, predominately and differentially, and the impact of stress and adversity on the health of women. Both of these research pillars include research activities funded by the National Institutes of Health, industry, and philanthropic resources, as well as cross-cutting academic collaborations. Each pillar incorporates structured educational programs and training fellowships to mentor and sponsor the next generation of investigators whose work focuses on the health of women.

Dr. Joffe’s contributions to clinical work, research, and mentoring have been recognized through the BWH Distinguished Clinician Award, the Thomas Clarkson Outstanding Clinical & Basic Science Research Award from the North American Menopause Society, and the HMS Department of Psychiatry Stuart T. Hauser MD PhD Mentorship Award.