Why do patients with active lupus have a low CRP?Although the erythrocyte sedimentation rate (ESR) is typically high in active lupus, C-reactive protein (CRP) is often normal. What’s particularly cool about this finding is that it lends insights into the mechanism of lupus and potentially its cause.The earliest report alluding to this discordance was published in 1951 by Alan Hill. He wondered whether CRP could be used to track disease activity in various non-infectious inflammatory con...

From blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer’s disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer’s diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.

Breeze through your next visit for insomnia. Learn how to comfortably approach insomnia and optimize sleep. We touch on specifics such as cognitive behavioral therapy for insomnia or the effects of various sleep-related drugs/supplements, and how to taper down from them. We are joined by Ashley E. Mason, PhD (UCSF).

In this episode, Dr. Janetta Arellano (Children’s Hospital of Orange County) joins us to take a deep dive into ADEM. We discuss the key features, diagnostic approach, and management of ADEM, with important pearls for distinguishing it from other neurologic emergencies.

Hold onto your pancreas! Diabetes technology is rapidly evolving, so pump up your knowledge with med-peds endocrinologist and Type 1 diabetes superstar Dr. Rebecca Vitale (UNC Chapel Hill). This discussion about CGMs, insulin pumps, and automated insulin delivery systems hits the sweet spot!

Become a master of pituitary incidentalomas. Learn about the hormonal workup and management of pituitary microadenomas, macroadenomas and empty sella syndrome and when surgery may be needed. We’re joined by Dr. Maria Fleseriu, @MariaFleseriu (Oregon Health and Science University)

In this episode, we explore how pediatricians can create safe, inclusive spaces for discussing sexual health. Our hosts review evidence-based recommendations for STI screening and treatment, emphasizing how to tailor care to the diverse needs of young patients. We also discuss practical approaches to communicating results, preserving confidentiality, and empowering youth with tools for STI prevention.

Don’t get caught treating high blood pressure like it is 2024. Dr. Jordy Cohen (@jordybc.bsky.social, University of Pennsylvania) guides us through the new hypertension guidelines.

Master cardiovascular disease prevention! Learn how to apply the new PREVENT risk calculator, use the CPR framework for risk reclassification, and interpret ApoB and Lp(a) in modern lipid management. We’re joined by Dr. Laurence Sperling to break down what’s new in ASCVD risk assessment and prevention.

Keep older adult patients on their feet, literally! Learn to map the Age-Friendly 5Ms Framework onto multifactorial risk factor assessment and management and incorporate other evidence-based fall prevention interventions with the expertise of an interdisciplinary team. We are joined by geriatrician Alyson Michener (@AlysonMichener University of Pennsylvania) and physical therapist Suzanne Zukoski (Good Shepherd Penn Partners).